Medical Tech Essay (Pre-analytical, analytical and post-analytical challenges on Paediatric Reference interval establishment) Essay Question: 1. Reference intervals provide valuable information to doctors in their interpretation of laboratory test results, and are important in patient diagnosis and making key clinical decisions. The reference interval serves as a benchmark with which to compare a patient’s test result. Currently, many pediatric laboratory test results are inappropriately interpreted using reference intervals obtained from adult populations, hospitalized pediatric populations, or outdated and/or inaccurate technology. Thus, many pediatric reference intervals used in diagnostic laboratories are incomplete and may not be suitable for clinical use. 2. Discuss the pre-analytical, analytical, and post-analytical challenges that can affect the establishment of pediatric reference intervals. Propose how you would overcome those challenges and provide relevant examples. (Your essay should include the rationale for establishing a pediatric reference interval, factors that can affect it, and any other considerations that are applicable.)
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